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It is 7.30pm and on the 13th floor of the Thomas Kemp tower at the Royal Sussex Hospital in Brighton, eight midwives wearing royal-blue scrubs are being briefed ahead of their nightshift.

Their lunchboxes put to one side, they sit where they can, sharing chairs and squeezing on to a desk.

During its early course, diabetic nephropathy often has no symptoms.

Symptoms can take 5 to 10 years to appear after the kidney damage begins.

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There are usually no specific symptoms of kidney disease until the damage is severe.

Signs of early kidney damage can develop in more than half the people with diabetes.

If left untreated, this could lead to more damage or kidney failure.

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Geneticists have by now identified a set of genes that regulate the SCN and thus the circadian rhythm among mammals.

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