The vaccines are based upon the Australian discovery that the major HPV capsid protein L1 can self assemble into virus-like particles (VLPs) when independently expressed in cultured cells, and induce high titres of type-specific and protective neutralising antibodies in animals.
The HPV vaccine was introduced in 2006, but immunisation rates have remained low despite an official recommendation from the Centers for Disease Control and Prevention, including a recommendation to vaccinate boys as well.
VLP based vaccines against the cancer causing HPV types 16 and 18, and against types 6 and 11 (which cause genital warts) are in current clinical trials.
Early results are promising, with vaccine providing 100 per cent protection (95%CI 90-100%) against persistent infection with HPV 16.
After three rounds of interaction, if there are girls keeping the light on for the candidate, and if he likes one of them, he succeeds in the match.
But if all twenty-four lights go off, the male loses boosted its popularity because of its unique approaching to dating, which well reflects changes happening to women in modern China.
Federal researchers found that the prevalence of HPV had fallen by 64 per cent in girls ages 14 to 19.